Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 3/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SLC34A1 | Q06495 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.33 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.33 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532209 | 0.78 | AMY1A (0.39) | PTGS1PTGS2AMY1APDE10AKDM4E | |
| SCHEMBL8471677 | 0.76 | AMY1A (0.38) | PTGS1PTGS2AMY1APDE10AKDM4E | |
| SCHEMBL9530825 | 0.76 | PTGS1 (0.47) | PTGS1PTGS2AMY1APDE10AKDM4E | |
| SCHEMBL13874013 | 0.69 | THRB (0.41) | PTGS1PTGS2AMY1AKDM4EPOLB | |
| SCHEMBL20924977 | 0.68 | ERN1 (0.43) | PTGS1PTGS2AMY1AKDM4EPOLB | |
| SCHEMBL1682483 | 0.67 | ERN1 (0.42) | PTGS1PTGS2AMY1AKDM4EPOLB | |
| SCHEMBL1682501 | 0.67 | USP8 (0.37) | AMY1APDE10AKDM4EPOLBALDH1A1 | |
| SCHEMBL10340365 | 0.66 | AMY1A (0.50) | AMY1AALDH1A1MAPTPRKAB2PRKAG1 | |
| SCHEMBL8474290 | 0.64 | ERN1 (0.41) | AMY1AKDM4EPOLBALDH1A1PDE2A | |
| SCHEMBL13184428 | 0.64 | SLC34A1 (0.53) | PDE10AKDM4EPOLBALDH1A1SLC34A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542872-A1 | HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES | MONSANTO COMPANY (US) | 1993-05-26 | — | — | EP | disclosed |