Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3198101 | 0.89 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL12438719 | 0.83 | MAPT (0.40) | ALDH1A1 | |
| SCHEMBL11849287 | 0.79 | KDM4E (0.34) | — | |
| SCHEMBL22260783 | 0.79 | ALDH1A1 (0.45) | ALDH1A1 | |
| SCHEMBL20043769 | 0.79 | ALDH1A1 (0.45) | ALDH1A1 | |
| SCHEMBL31265110 | 0.77 | ALDH1A1 (0.41) | ALDH1A1 | |
| SCHEMBL13286401 | 0.76 | HSD11B1 (0.30) | — | |
| SCHEMBL9527329 | 0.74 | ALDH1A1 (0.56) | ALDH1A1 | |
| SCHEMBL12920697 | 0.73 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL5398064 | 0.73 | MAP3K14 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220873-B1 | Fused bicyclic imides with psychotropic activity | AMERICAN HOME PROD (US) | 1993-11-24 | — | — | EP | disclosed |
| EP-0220873-A1 | Fused bicyclic imides with psychotropic activity | AMERICAN HOME PRODUCTS CORPORATION (US) | 1987-05-06 | — | — | EP | disclosed |