SCHEMBL25401668

SCHEMBL25401668

CC(=O)c1cc(Br)c2ccccn12

nearest known ligand 0.62

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ BAZ2B Q9UIF8 11/20 0.62
▸ BAZ2A Q9UIF9 11/20 0.62
▸ BRD4 O60885 2/20 0.57
▸ BRD9 Q9H8M2 2/20 0.57
▸ BRD2 P25440 1/20 0.57
▸ BRD3 Q15059 1/20 0.57
▸ MAPT P10636 4/20 0.51
▸ THRB P10828 1/20 0.51
▸ TP53 P04637 3/20 0.49
▸ FNTA P49354 2/20 0.44
▸ FNTB P49356 2/20 0.44
▸ KDM4E B2RXH2 1/20 0.43
▸ NPSR1 Q6W5P4 1/20 0.43
▸ RXFP1 Q9HBX9 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29412239 0.81 MAPT (0.68) BAZ2BBAZ2ABRD4BRD9BRD2
SCHEMBL7439300 0.81 BAZ2B (0.64) BAZ2BBAZ2ABRD4BRD9BRD2
SCHEMBL25402450 0.80 FNTA (0.68) BAZ2BBAZ2ABRD4BRD2BRD3
SCHEMBL26302103 0.79 BAZ2B (0.75) BAZ2BBAZ2ABRD4BRD9BRD2
SCHEMBL25400578 0.78 BAZ2B (0.45) BAZ2BBAZ2ABRD4BRD9BRD2
SCHEMBL9531095 0.78 FNTA (0.69) BAZ2BBAZ2ABRD4BRD9BRD2
SCHEMBL26302091 0.76 BAZ2B (0.74) BAZ2BBAZ2ABRD4BRD9BRD2
SCHEMBL29547493 0.75 FNTA (0.54) BAZ2BBAZ2AMAPTTP53FNTA
SCHEMBL24304134 0.74 TP53 (0.63) BAZ2BBAZ2ABRD4BRD9BRD2
SCHEMBL24510741 0.74 BAZ2B (0.57) BAZ2BBAZ2ABRD9TP53FNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4233864-B1 COMPOSITION COMPRISING AN INDOLIZINE DERIVATIVE AND A CYCLIC DINUCLEOTIDE AS ACTIVE AGENTS UNIV AJOU IND ACADEMIC COOP FOUND (KR) 2025-02-12 — — EP disclosed
US-20230390319-A1 INTERFERON GENE STIMULATOR COMPOSITION COMPRISING INDOLIZINE DERIVATIVE AS ACTIVE INGREDIENT KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2023-12-07 — — US disclosed
EP-4233864-A1 INTERFERON GENE STIMULATOR COMPOSITION COMPRISING INDOLIZINE DERIVATIVE AS ACTIVE INGREDIENT Ajou University Industry-Academic Cooperation Foundation (KR) 2023-08-30 — — EP disclosed
EP-4233864-A1 INTERFERON GENE STIMULATOR COMPOSITION COMPRISING INDOLIZINE DERIVATIVE AS ACTIVE INGREDIENT Ajou University Industry-Academic Cooperation Foundation (KR) 2023-08-30 — — EP disclosed
WO-2022086260-A1 INTERFERON GENE STIMULATOR COMPOSITION COMPRISING INDOLIZINE DERIVATIVE AS ACTIVE INGREDIENT 아주대학교산학협력단 2022-04-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230390319-A1 INTERFERON GENE STIMULATOR COMPOSITION COMPRISING INDOLIZINE DERIVATIVE AS ACTIVE INGREDIENT STING1, IRF3, IFNG BAZ2B 4487/4885BAZ2A 4020/4885BRD4 3042/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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