Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.51 |
| ▸ | HTR3A | P46098 | 2/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9531740 | 0.99 | CHRNA7 (0.50) | CHRNA7HTR3ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9748210 | 0.79 | CHRNA7 (0.53) | CHRNA7HTR3ACHRNB2CHRNB4CHRNA3 | |
| SCHEMBL9531570 | 0.78 | CHRNA7 (0.52) | CHRNA7 | |
| SCHEMBL9532171 | 0.76 | HTR4 (0.59) | HTR3ACHRNB2CHRNA3CHRNA4HTR4 | |
| SCHEMBL7329253 | 0.74 | CNR2 (0.45) | HTR4 | |
| SCHEMBL1567298 | 0.73 | HTR3A (0.60) | CHRNA7HTR3ACHRNB2CHRNA3CHRNA4 | |
| Hydrochloric Acid SCHEMBL7299025 | 0.71 | CHRNA7 (0.52) | CHRNA7HTR3AHTR4 | |
| SCHEMBL7301916 | 0.71 | CHRNA7 (0.51) | CHRNA7 | |
| SCHEMBL492411 | 0.70 | CHRNA7 (0.58) | CHRNA7HTR3A | |
| SCHEMBL30117759 | 0.70 | CHRNA7 (0.53) | CHRNA7HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289170-B1 | AZABICYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1993-06-23 | — | — | EP | claimed |
| EP-0289170-A2 | Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1988-11-02 | — | — | EP | claimed |