SCHEMBL9531339

SCHEMBL9531339

COc1ccc2c(c1)SCCC2CN(C)CCc1cccc(F)c1

nearest known ligand 0.57

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 2/20 0.57
SLC6A4 P31645 2/20 0.57
TAAR1 Q96RJ0 1/20 0.41
SIGMAR1 Q99720 2/20 0.41
KDM4E B2RXH2 1/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9533763 0.88 HTR1A (0.43) HTR1ASLC6A4TAAR1SIGMAR1
SCHEMBL9535109 0.81 DRD2 (0.46) HTR1ASLC6A4ALDH1A1
Hydrochloric Acid SCHEMBL9523522 0.81 HTR1A (0.69) HTR1ASLC6A4
Hydrochloric Acid SCHEMBL9521599 0.72 HTR1A (0.69) HTR1ASLC6A4TAAR1SIGMAR1
Hydrochloric Acid SCHEMBL9720804 0.72 HTR1A (0.57) HTR1ASLC6A4SIGMAR1
Hydrochloric Acid SCHEMBL9519925 0.71 HTR1A (0.51) HTR1ASLC6A4
Hydrochloric Acid SCHEMBL9520941 0.71 SLC6A4 (0.80) HTR1ASLC6A4
Hydrochloric Acid SCHEMBL9523511 0.71 HTR1A (0.55) HTR1ASLC6A4
Hydrochloric Acid SCHEMBL9522167 0.70 HTR1A (0.57) HTR1ASLC6A4
Hydrochloric Acid SCHEMBL9466633 0.70 SLC6A4 (0.59) HTR1ASLC6A4KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0560794-A1 SUBSTITUTED 1,3-OXATHIOLANES AND SUBSTITUTED 1,3-DITHIOLANES WITH ANTIVIRAL PROPERTIES. IAF BIOCHEM INT (CA) 1993-09-22 EP disclosed