Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9531339 | 0.88 | HTR1A (0.57) | HTR1ASLC6A4TAAR1SIGMAR1 | |
| SCHEMBL9535109 | 0.81 | DRD2 (0.46) | HTR1ASLC6A4DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL9464783 | 0.79 | HTR1A (0.51) | HTR1ASLC6A4DRD2DRD3KCNH2 | |
| Hydrochloric Acid SCHEMBL9464703 | 0.73 | HTR1A (0.46) | HTR1ASLC6A4DRD2DRD3KCNH2 | |
| Hydrochloric Acid SCHEMBL9465028 | 0.72 | CYP19A1 (0.46) | HTR1ASLC6A4DRD2DRD3KCNH2 | |
| Hydrochloric Acid SCHEMBL9720804 | 0.72 | HTR1A (0.57) | HTR1ASLC6A4SIGMAR1 | |
| SCHEMBL25833563 | 0.71 | TAAR1 (0.61) | DRD2DRD3TAAR1SIGMAR1AOC3 | |
| Hydrochloric Acid SCHEMBL9519925 | 0.71 | HTR1A (0.51) | HTR1ASLC6A4 | |
| SCHEMBL9533768 | 0.70 | HTR1A (0.38) | HTR1ASLC6A4 | |
| Hydrochloric Acid SCHEMBL9464551 | 0.70 | SLC6A4 (0.46) | HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396620-B1 | AMINOMETHYL-CHROMAN AND -THIOCHROMAN COMPOUNDS | ABBOTT LABORATORIES (US) | 1993-08-11 | — | — | EP | claimed |