Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8340736 | 0.91 | PTGS2 (0.39) | PTGS2L3MBTL1CTDSP1MAPTCRHBP | |
| SCHEMBL8490863 | 0.86 | KMT2A (0.39) | PTGS2L3MBTL1CTDSP1MAPTCRHBP | |
| SCHEMBL9534866 | 0.79 | PTGS2 (0.39) | PTGS2L3MBTL1CTDSP1MAPTCRHBP | |
| SCHEMBL9533583 | 0.76 | TLR3 (0.43) | PTGS2L3MBTL1CTDSP1MAPTKCNH2 | |
| SCHEMBL13592372 | 0.73 | — | — | |
| SCHEMBL9531520 | 0.72 | HIF1A (0.46) | PTGS2L3MBTL1CTDSP1MAPTKMT2A | |
| SCHEMBL9531639 | 0.71 | KMT2A (0.42) | PTGS2L3MBTL1CTDSP1MAPTKCNH2 | |
| SCHEMBL10656850 | 0.68 | MAPT (0.43) | PTGS2MAPTALDH1A1LMNA | |
| SCHEMBL2565915 | 0.67 | PTGS2 (0.51) | PTGS2L3MBTL1CTDSP1MAPTKCNH2 | |
| SCHEMBL11742757 | 0.64 | PTGS2 (0.46) | PTGS2L3MBTL1CTDSP1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277836-B1 | THIAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-06-02 | — | — | EP | disclosed |
| US-4873255-A | REDUCE BLOOD GLUCOSE AND BLOOD LIPID LEVELS | SANKYO COMPANY LIMITED (JP) | 1989-10-10 | — | — | US | disclosed |
| EP-0277836-A1 | Thiazolidinone derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1988-08-10 | — | — | EP | disclosed |