Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | TLR3 | O15455 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9531441 | 0.79 | PTGS2 (0.42) | PTGS2L3MBTL1CTDSP1MAPTALDH1A1 | |
| SCHEMBL9533583 | 0.77 | TLR3 (0.43) | PTGS2L3MBTL1CTDSP1TLR3MAPT | |
| SCHEMBL9531520 | 0.76 | HIF1A (0.46) | PTGS2L3MBTL1CTDSP1TLR3MAPT | |
| SCHEMBL8340736 | 0.76 | PTGS2 (0.39) | PTGS2L3MBTL1CTDSP1MAPTALDH1A1 | |
| SCHEMBL9533103 | 0.72 | KMT2A (0.47) | PTGS2L3MBTL1CTDSP1MAPTPOLB | |
| SCHEMBL8490863 | 0.72 | KMT2A (0.39) | PTGS2L3MBTL1CTDSP1MAPTPOLB | |
| SCHEMBL9632320 | 0.69 | TLR3 (0.41) | PTGS2L3MBTL1CTDSP1TLR3MAPT | |
| SCHEMBL9632014 | 0.68 | TLR3 (0.45) | PTGS2TLR3MAPTPOLBALDH1A1 | |
| SCHEMBL7533888 | 0.68 | KCNH2 (0.38) | PTGS2L3MBTL1CTDSP1MAPTPOLB | |
| SCHEMBL6987818 | 0.65 | TLR3 (0.46) | PTGS2TLR3MAPTALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0277836-B1 | THIAZOLIDINONE DERIVATIVES, THEIR PREPARATION AND THEIR USE | Sankyo Company Limited (JP) | 1993-06-02 | — | — | EP | disclosed |
| US-4873255-A | REDUCE BLOOD GLUCOSE AND BLOOD LIPID LEVELS | SANKYO COMPANY LIMITED (JP) | 1989-10-10 | — | — | US | disclosed |
| EP-0277836-A1 | Thiazolidinone derivatives, their preparation and their use | Sankyo Company Limited (JP) | 1988-08-10 | — | — | EP | disclosed |