Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9531441 | 0.91 | PTGS2 (0.42) | PTGS2MAPTL3MBTL1CRHBPCRHR2 | |
| SCHEMBL8490863 | 0.84 | KMT2A (0.39) | PTGS2MAPTL3MBTL1CRHBPCRHR2 | |
| SCHEMBL9534866 | 0.76 | PTGS2 (0.39) | PTGS2MAPTL3MBTL1CRHBPCRHR2 | |
| SCHEMBL9632107 | 0.74 | MAPT (0.60) | PTGS2MAPTKMT2AMEN1 | |
| SCHEMBL8980424 | 0.73 | KMT2A (0.44) | PTGS2MAPTL3MBTL1CRHBPCRHR2 | |
| SCHEMBL9533583 | 0.72 | TLR3 (0.43) | PTGS2MAPTL3MBTL1CTDSP1KMT2A | |
| SCHEMBL10641737 | 0.72 | MAPT (0.47) | PTGS2MAPTCRHBPCRHR2KMT2A | |
| SCHEMBL10638977 | 0.72 | MAPT (0.45) | PTGS2MAPTKMT2AGAAMEN1 | |
| SCHEMBL9632315 | 0.71 | KMT2A (0.42) | MAPTL3MBTL1CRHBPCRHR2KMT2A | |
| SCHEMBL8490238 | 0.70 | PTGS1 (0.32) | PTGS2MAPTKMT2AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0670300-B1 | Process for the preparation of allyl quinone derivatives, and intermediates | EISAI CO LTD (JP) | 1999-06-23 | — | — | EP | disclosed |
| US-5874611-A | Butenyl hydroquinone derivatives | EISAI CHEMICAL CO., LTD. (JP) | 1999-02-23 | — | — | US | disclosed |
| WO-1999006392-A1 | METHOD FOR PREPARING 2H-1 BENZOPYRANES AND SYNTHESIS INTERMEDIATES | RHODIA CHIMIE (FR) | 1999-02-11 | — | — | WO | disclosed |
| US-5565586-A | Oxidative process for the preparation of allyl quinone derivatives | EISAI CHEMICAL CO., LTD. (JP) | 1996-10-15 | — | — | US | disclosed |
| EP-0670300-A2 | Process for the preparation of allyl quinone derivatives, and intermediates | EISAI CHEMICAL CO., LTD. (JP) | 1995-09-06 | — | — | EP | disclosed |