Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 11/20 | 0.46 |
| ▸ | PLA2G10 | O15496 | 4/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.46 |
| ▸ | PLA2G5 | P39877 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.31 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.31 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.31 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9798948 | 1.00 | PLA2G2A (0.46) | PLA2G2APLA2G10PLA2G1BPLA2G5CYP1A2 | |
| SCHEMBL9798365 | 1.00 | PLA2G2A (0.46) | PLA2G2APLA2G10PLA2G1BPLA2G5CYP1A2 | |
| SCHEMBL9799022 | 1.00 | PLA2G2A (0.46) | PLA2G2APLA2G10PLA2G1BPLA2G5CYP1A2 | |
| SCHEMBL9670952 | 0.84 | PLA2G2A (0.40) | PLA2G2APLA2G10PLA2G1BPLA2G5CYP1A2 | |
| SCHEMBL9528937 | 0.82 | PLA2G2A (0.34) | PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL9528946 | 0.82 | PLA2G2A (0.34) | PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL9531777 | 0.81 | PLA2G2A (0.39) | PLA2G2APLA2G10PLA2G1BPLA2G5FAAH | |
| SCHEMBL9799057 | 0.81 | PLA2G2A (0.47) | PLA2G2APLA2G10PLA2G1BPLA2G5CYP1A2 | |
| SCHEMBL9799059 | 0.81 | PLA2G2A (0.47) | PLA2G2APLA2G10PLA2G1BPLA2G5CYP1A2 | |
| SCHEMBL2233937 | 0.80 | PLA2G2A (0.47) | PLA2G2APLA2G10PLA2G1BPLA2G5HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068340-A | Antagonist of platelet activating factor for treatment of asthma, inflammation or shock | SANKYO COMPANY, LIMITED (JP) | 1991-11-26 | — | — | US | disclosed |
| EP-0238202-A2 | Glycerol derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1987-09-23 | — | — | EP | disclosed |