Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.48 |
| ▸ | HNF4A | P41235 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | FABP3 | P05413 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18825620 | 0.94 | BCAT2 (0.59) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL229441 | 0.93 | BCAT2 (0.63) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL3297211 | 0.85 | BCAT2 (0.53) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL29697585 | 0.83 | BCAT2 (0.47) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL29697586 | 0.83 | BCAT2 (0.47) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL28640320 | 0.83 | SLC6A3 (0.64) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL31517118 | 0.82 | HNF4A (0.61) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL27592177 | 0.82 | BCAT2 (0.59) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL1479704 | 0.82 | HNF4A (0.61) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 | |
| SCHEMBL1580001 | 0.82 | SLC6A3 (0.49) | BCAT2MEN1KMT2ASMN1; SMN2CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289170-B1 | AZABICYCLIC COMPOUNDS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1993-06-23 | — | — | EP | disclosed |
| US-4882327-A | NERVOUS SYSTEM DISORDERS | BEECHAM GROUP P.L.C. (GB) | 1989-11-21 | — | — | US | disclosed |
| EP-0289170-A2 | Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1988-11-02 | — | — | EP | disclosed |