SCHEMBL28640320

SCHEMBL28640320

O=C(Cl)c1ccccc1-c1ccc(Cl)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 3/20 0.64
SLC6A4 P31645 2/20 0.64
BCAT2 O15382 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
PTGS2 P35354 2/20 0.46
PTGS1 P23219 1/20 0.46
ALDH1A1 P00352 1/20 0.45
ALOX15 P16050 1/20 0.45
FGFR1 P11362 1/20 0.44
SRC P12931 1/20 0.44
FGFR2 P21802 1/20 0.44
FGFR4 P22455 1/20 0.44
FGFR3 P22607 1/20 0.44
NR4A1 P22736 1/20 0.43
CYP2C19 P33261 1/20 0.43
CYP1A2 P05177 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
BRS3 P32247 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10631889 0.86 SLC6A4 (0.66) SLC6A3SLC6A4BCAT2TDP1PTGS2
SCHEMBL18825620 0.86 BCAT2 (0.59) SLC6A3SLC6A4BCAT2ALDH1A1ALOX15
SCHEMBL229441 0.85 BCAT2 (0.63) SLC6A3SLC6A4BCAT2ALDH1A1ALOX15
SCHEMBL496623 0.84 SLC6A4 (0.64) SLC6A3SLC6A4BCAT2ALDH1A1ALOX15
SCHEMBL29697586 0.84 BCAT2 (0.47) SLC6A3SLC6A4BCAT2ALDH1A1ALOX15
SCHEMBL29697585 0.84 BCAT2 (0.47) SLC6A3SLC6A4BCAT2ALDH1A1ALOX15
SCHEMBL9532086 0.83 BCAT2 (0.55) SLC6A3SLC6A4BCAT2ALDH1A1ALOX15
SCHEMBL1497097 0.82 SLC6A3 (0.67) SLC6A3SLC6A4BCAT2TDP1PTGS2
SCHEMBL7605043 0.82 SLC6A3 (0.62) SLC6A3SLC6A4BCAT2PTGS2PTGS1
SCHEMBL8900629 0.82 SLC6A3 (0.60) SLC6A3SLC6A4BCAT2TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109970571-B Synthesis process of 2- (4-chlorphenyl) aniline 安徽丰乐农化有限责任公司 2021-10-19 CN claimed
CN-116444444-A Method for preparing 2-substituted quinazolinone compound 盐城工业职业技术学院 2023-07-18 CN disclosed
CN-109970571-B Synthesis process of 2- (4-chlorphenyl) aniline 安徽丰乐农化有限责任公司 2021-10-19 CN disclosed