Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9698943 | 0.90 | DRD2 (0.51) | HRH3DRD2DRD3LTA4HMAOB | |
| Hydrochloric Acid SCHEMBL9528697 | 0.89 | DRD2 (0.50) | HRH3DRD2DRD3LTA4HMAOB | |
| SCHEMBL7323189 | 0.89 | HRH3 (0.57) | HRH3DRD2LTA4HALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL7319312 | 0.88 | HRH3 (0.56) | HRH3DRD2LTA4HALDH1A1TSHR | |
| SCHEMBL10690668 | 0.85 | HRH3 (0.53) | HRH3LTA4HALDH1A1KMT2AKDM4E | |
| Oxalic Acid SCHEMBL10692238 | 0.81 | KDM4E (0.55) | HRH3ALDH1A1KMT2AKDM4ELMNA | |
| SCHEMBL9698304 | 0.81 | HRH3 (0.45) | HRH3DRD2DRD3ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL27351881 | 0.80 | HRH3 (0.44) | HRH3DRD2DRD3ALDH1A1TSHR | |
| Oxalic Acid SCHEMBL6987238 | 0.79 | KDM4E (0.49) | HRH3ALDH1A1KMT2AKDM4ELMNA | |
| Oxalic Acid SCHEMBL6990511 | 0.79 | KDM4E (0.49) | HRH3ALDH1A1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542844-A1 | 3-SUBSTITUTED PIPERIDINE DERIVATIVES | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-05-26 | — | — | EP | claimed |