Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690668 | 0.96 | HRH3 (0.53) | KDM4EKMT2AALDH1A1LMNAGAA | |
| SCHEMBL10692724 | 0.82 | HRH3 (0.49) | KDM4EKMT2AALDH1A1LMNAGAA | |
| SCHEMBL10692369 | 0.81 | KMT2A (0.53) | KDM4EKMT2AALDH1A1LMNAGAA | |
| SCHEMBL9532091 | 0.81 | HRH3 (0.50) | KDM4EKMT2AALDH1A1LMNAGAA | |
| SCHEMBL9698943 | 0.79 | DRD2 (0.51) | HRH3 | |
| SCHEMBL10690170 | 0.78 | KMT2A (0.50) | KDM4EKMT2AALDH1A1LMNAGAA | |
| Hydrochloric Acid SCHEMBL9528697 | 0.78 | DRD2 (0.50) | HRH3 | |
| Oxalic Acid SCHEMBL10695599 | 0.78 | KDM4E (0.59) | KDM4EKMT2AALDH1A1LMNAGAA | |
| SCHEMBL10697150 | 0.75 | KDM4E (0.56) | KDM4EKMT2AALDH1A1LMNAGAA | |
| Oxalic Acid SCHEMBL6987238 | 0.75 | KDM4E (0.49) | KDM4EKMT2AALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0252876-A1 | Hydrogenated 1-phenoxyalkylpyridine-3-carboxylic-acid compounds | CIBA-GEIGY AG (CH) | 1988-01-13 | — | — | EP | disclosed |