Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.47 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.45 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527829 | 0.97 | MAPK1 (0.55) | MAPK1TBXAS1MMP2CYP1A2CYP3A4 | |
| SCHEMBL9527952 | 0.89 | ALDH1A1 (0.49) | MAPK1TBXAS1MAPTKDM4EALDH1A1 | |
| SCHEMBL9527966 | 0.82 | ALDH1A1 (0.54) | MAPK1CYP3A4KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL9532138 | 0.81 | TBXAS1 (0.55) | MAPK1TBXAS1MAPTKDM4EALDH1A1 | |
| SCHEMBL9532347 | 0.81 | ABCB1 (0.53) | TBXAS1MAPTALDH1A1SMN1; SMN2TBXA2R | |
| SCHEMBL9532300 | 0.79 | TBXAS1 (0.57) | TBXAS1KDM4EALDH1A1SMN1; SMN2TBXA2R | |
| SCHEMBL9532489 | 0.79 | CYP11B1 (0.52) | MAPK1TBXAS1CYP1A2CYP3A4KDM4E | |
| SCHEMBL9529775 | 0.79 | TBXAS1 (0.50) | MAPK1TBXAS1MAPTRXFP1ALDH1A1 | |
| SCHEMBL9528147 | 0.79 | TBXAS1 (0.55) | TBXAS1CYP1A2CYP3A4CYP2D6CYP1A1 | |
| SCHEMBL9532150 | 0.79 | TBXAS1 (0.55) | TBXAS1CYP1A2CYP3A4CYP2D6CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4971985-A | ANTIISCHEMIC AGENTS, CARDIOVASCULAR DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |