Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.43 |
| ▸ | PPARA | Q07869 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532848 | 0.88 | PPARG (0.50) | PPARGPPARAKDM4EMAPTALDH1A1 | |
| SCHEMBL9532701 | 0.81 | PPARG (0.51) | PPARGPPARAKDM4EALDH1A1LMNA | |
| SCHEMBL17411300 | 0.79 | HTR1A (0.51) | HTR1A | |
| SCHEMBL8264178 | 0.73 | QDPR (0.59) | — | |
| SCHEMBL6637148 | 0.73 | HTR1A (0.48) | HTR1A | |
| SCHEMBL7861680 | 0.71 | TSHR (0.73) | KDM4EMAPTALDH1A1LMNAGAA | |
| SCHEMBL8352095 | 0.69 | MEN1 (0.59) | PPARGPPARAKDM4EMAPTALDH1A1 | |
| SCHEMBL6604425 | 0.68 | HTR1A (0.46) | PPARGPPARAKDM4EMAPTALDH1A1 | |
| SCHEMBL7369144 | 0.68 | KDM4E (0.45) | KDM4EMAPTALDH1A1LMNAALOX15 | |
| SCHEMBL14141231 | 0.67 | L3MBTL1 (0.48) | ALDH1A1ALOX15TSHRHTR1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556342-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYOGYSZERKUTATO INTEZET K.V. (HU) | 1993-08-25 | — | — | EP | disclosed |
| WO-1992007854-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYÓGYSZERKUTATÓ INTÉZET KV. (HU) | 1992-05-14 | — | — | WO | disclosed |