Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9531466 | 0.86 | SIGMAR1 (0.34) | MAOBKDM4EGAASIGMAR1KDM1A | |
| SCHEMBL9530955 | 0.81 | KMT2A (0.38) | KDM4EGAANPSR1PRNPPPARG | |
| SCHEMBL9532323 | 0.79 | MAOB (0.36) | MAOBKDM4ENPSR1SIGMAR1HTR2A | |
| SCHEMBL7883341 | 0.76 | MAOB (0.39) | MAOBSIGMAR1HTR2AALDH1A1HTR2C | |
| SCHEMBL9531785 | 0.73 | SIGMAR1 (0.35) | MAOBSIGMAR1KDM1A | |
| SCHEMBL9531388 | 0.70 | ALOX12 (0.36) | MAOBKDM4EGAANPSR1PRNP | |
| SCHEMBL9532397 | 0.68 | NPSR1 (0.37) | MAOBKDM4EGAANPSR1PRNP | |
| SCHEMBL11256078 | 0.66 | SIGMAR1 (0.44) | NPSR1PPARGSIGMAR1HTR2AALDH1A1 | |
| SCHEMBL9533561 | 0.66 | HTR1A (0.33) | SIGMAR1HTR2B | |
| SCHEMBL7549093 | 0.65 | SIGMAR1 (0.44) | MAOBSIGMAR1HTR2AALDH1A1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0314852-B1 | Process for the preparation of 1-substituted imidazole-carbonic acid and derivatives | CIBA GEIGY AG (CH) | 1993-11-18 | — | — | EP | disclosed |
| US-4921955-A | Process for the synthesis of 1-substituted imidazole-5-carboxylic acids and carboxylic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1990-05-01 | — | — | US | disclosed |
| EP-0314852-A2 | Process for the preparation of 1-substituted imidazole-carbonic acid and derivatives | CIBA-GEIGY AG (CH) | 1989-05-10 | — | — | EP | disclosed |