Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 3/20 | 0.55 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP14 | P50281 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL29911372 | 1.00 | ACP3 (0.55) | ACP3PTK2BL3MBTL1HDAC8HDAC6 | |
| SCHEMBL22658020 | 0.93 | ACP3 (0.50) | ACP3PTK2BL3MBTL1HDAC8HDAC6 | |
| Phosphoric Acid SCHEMBL29175024 | 0.91 | ACP3 (0.48) | ACP3PTK2BL3MBTL1HDAC8HDAC6 | |
| Phosphoric Acid SCHEMBL27538516 | 0.89 | CYP1A2 (0.56) | ACP3PTK2BL3MBTL1HDAC8HDAC6 | |
| SCHEMBL29051197 | 0.88 | CYP2A6 (0.46) | ACP3PTK2BL3MBTL1HDAC8HDAC6 | |
| SCHEMBL28712039 | 0.88 | CA1 (0.47) | ACP3PTK2BL3MBTL1HDAC8HDAC6 | |
| SCHEMBL27902996 | 0.88 | ACP3 (0.46) | ACP3PTK2BL3MBTL1HDAC8HDAC6 | |
| SCHEMBL25302086 | 0.87 | ALDH1A1 (0.59) | L3MBTL1CA12CA2CYP1A2PTPN1 | |
| SCHEMBL29350007 | 0.87 | ALDH1A1 (0.59) | L3MBTL1CA12CA2CYP1A2PTPN1 | |
| SCHEMBL27953 | 0.87 | ALDH1A1 (0.59) | L3MBTL1CA12CA2CYP1A2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 255 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118878452-B | Isoindolinone derived unsaturated imine compound, synthesis method thereof and application thereof in anti-tumor activity | 徐州市第一人民医院 | 2025-01-24 | — | — | CN | claimed |
| CN-118955508-A | Alpha-indolylpyrrolo [1,2-a ] indole derivative and preparation method thereof | 浙江大学 | 2024-11-15 | — | — | CN | claimed |
| CN-118878452-A | Isoindolinone derived unsaturated imine compound, synthesis method thereof and application thereof in anti-tumor activity | 徐州市第一人民医院 | 2024-11-01 | — | — | CN | claimed |
| CN-113173925-B | Benzoxoepinoindole derivative and preparation method thereof | 浙江大学 | 2022-11-11 | — | — | CN | claimed |
| US-11440871-B2 | Zuclomiphene salts and crystalline forms thereof | APOTEX INC. (CA) | 2022-09-13 | — | — | US | claimed |
| CN-108409746-B | Chiral oxo spiro indole compound containing pyrrole or indolocarbazacycloalkane structure, racemate thereof and preparation method | 中山大学 | 2021-08-24 | — | — | CN | claimed |
| CN-113173925-A | Benzoxoepinoindole derivative and preparation method thereof | 浙江大学 | 2021-07-27 | — | — | CN | claimed |
| US-20210147338-A1 | Zuclomiphene Salts and Crystalline Forms Thereof | THE BANK OF NOVA SCOTIA (CA) | 2021-05-20 | — | — | US | claimed |
| US-9914696-B2 | Clomiphene synthesis using a single solvent | REPROS THERAPEUTICS INC. (US) | 2018-03-13 | — | — | US | claimed |
| US-20170073302-A1 | CLOMIPHENE SYNTHESIS USING A SINGLE SOLVENT | REPROS THERAPEUTICS INC. (US) | 2017-03-16 | — | — | US | claimed |
| EP-3116488-A1 | CLOMIPHENE SYNTHESIS USING A SINGLE SOLVENT | Repros Therapeutics Inc. (US) | 2017-01-18 | — | — | EP | claimed |
| EP-3015453-B1 | Process for the preparation of Clomiphene | ITALIANA SINT SPA (IT) | 2016-10-12 | — | — | EP | claimed |
| US-20160152551-A1 | PROCESS FOR THE PREPARATION OF CLOMIPHENE | F.I.S.- FABBRICA ITALIANA SINTETICI S.P.A (IT) | 2016-06-02 | — | — | US | claimed |
| EP-3015453-A1 | Process for the preparation of Clomiphene | F.I.S.- Fabbrica Italiana Sintetici S.p.A. (IT) | 2016-05-04 | — | — | EP | claimed |
| WO-2015138340-A1 | CLOMIPHENE SYNTHESIS USING A SINGLE SOLVENT | REPROS THERAPEUTICS INC. (US) | 2015-09-17 | — | — | WO | claimed |
| EP-2155756-B1 | PROCESSES FOR THE PREPARATION OF CLOPIDOGREL | WOCKHARDT LTD (IN) | 2015-08-05 | — | — | EP | claimed |
| CN-102690227-A | Optical active tetrahydropyridine derivative and preparation method thereof | UNIV ZHEJIANG | 2012-09-26 | — | — | CN | claimed |
| EP-4641591-A1 | FOAM MOLDING COMPOSITION, FOAM-MOLDED BODY, FOAMED ELECTRIC WIRE, MANUFACTURING METHOD FOR FOAM-MOLDED BODY, MANUFACTURING METHOD FOR ELECTRIC WIRE, AND IN-VEHICLE NETWORK CABLE | Daikin Industries, Ltd. (JP) | 2025-10-29 | — | — | EP | disclosed |
| US-3941795-A | ANTIHISTAMINE, ANTIALLERGY, BRONCHODILATOR | RICHARDSON-MERRELL INC. (US) | 1976-03-02 | — | — | US | disclosed |
| US-3931197-A | ANTIHISTAMINE, ANTIALLERGY, BRONCHODILATOR | RICHARDSON-MERRELL INC. (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11440871-B2 | Zuclomiphene salts and crystalline forms thereof | ZP1, ZYX, ALPP | ACP3 6/4885PTK2B 1379/4885L3MBTL1 915/4885 |
| US-20160152551-A1 | PROCESS FOR THE PREPARATION OF CLOMIPHENE | CYP19A1, CYP11A1, SI | ACP3 8/4885PTK2B 2874/4885L3MBTL1 4593/4885 |
| US-20210147338-A1 | Zuclomiphene Salts and Crystalline Forms Thereof | ZP1, ZYX, ALPP | ACP3 7/4885PTK2B 1374/4885L3MBTL1 957/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.