Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 11/20 | 0.42 |
| ▸ | ADH1C | P00326 | 8/20 | 0.39 |
| ▸ | ADH4 | P08319 | 2/20 | 0.39 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
| ▸ | ADH1B | P00325 | 2/20 | 0.33 |
| ▸ | ADH7 | P40394 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL95341 | 0.73 | ADH1A (0.33) | ADH1AADH1CADH4 | |
| SCHEMBL12918857 | 0.73 | ADH1A (0.32) | ADH1AADH1C | |
| SCHEMBL14199751 | 0.71 | ADH1A (0.35) | ADH1AADH1CSLC29A1 | |
| SCHEMBL3957150 | 0.71 | ADH1A (0.44) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL10170019 | 0.71 | ADH1A (0.39) | ADH1AADH1CADH4 | |
| SCHEMBL27705383 | 0.67 | ADH1B (0.40) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL73403 | 0.67 | ADH1B (0.40) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL5543967 | 0.67 | ADH1B (0.40) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL10620802 | 0.67 | TSHR (0.40) | — | |
| SCHEMBL10170018 | 0.67 | SIGMAR1 (0.38) | ADH1AADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8362252-B2 | Carbostyril compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-01-29 | — | — | US | disclosed |
| EP-1797082-B1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2012-08-29 | — | — | EP | disclosed |
| EP-2426128-A1 | Carbostyril compound | Otsuka Pharmaceutical Co., Limited (JP) | 2012-03-07 | — | — | EP | disclosed |
| US-20100261705-A1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. | 2010-10-14 | — | — | US | disclosed |
| US-7777038-B2 | Carbostyril compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-08-17 | — | — | US | disclosed |
| US-20090326008-A1 | NF-kappa B Inhibitor | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2009-12-31 | — | — | US | disclosed |
| US-20070179173-A1 | Carbostyril compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-08-02 | — | — | US | disclosed |
| EP-1797082-A1 | CARBOSTYRIL COMPOUND | Otsuka Pharmaceutical Company, Limited (JP) | 2007-06-20 | — | — | EP | disclosed |
| WO-2006035954-A1 | CARBOSTYRIL COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-04-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090326008-A1 | NF-kappa B Inhibitor | NFKBIA, NFKB2, IKBKB | ADH1A 2734/4885ADH1C 2430/4885ADH4 2644/4885 |
| US-20070179173-A1 | Carbostyril compound | GTF2F1, F3, GTF2F2 | ADH1A 848/4885ADH1C 786/4885ADH4 752/4885 |
| US-20100261705-A1 | CARBOSTYRIL COMPOUND | GTF2F1, F3, GTF2F2 | ADH1A 848/4885ADH1C 786/4885ADH4 752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.