Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 11/20 | 0.44 |
| ▸ | ADH1C | P00326 | 8/20 | 0.42 |
| ▸ | ADH4 | P08319 | 2/20 | 0.40 |
| ▸ | ADH1B | P00325 | 2/20 | 0.40 |
| ▸ | ADH7 | P40394 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15285433 | 0.84 | ADH1A (0.39) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL29951006 | 0.78 | ADH1A (0.48) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL10170019 | 0.77 | ADH1A (0.39) | ADH1AADH1CADH4ALDH1A1SMN1; SMN2 | |
| SCHEMBL29954517 | 0.76 | ADH1A (0.45) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL30657708 | 0.75 | ADH1A (0.50) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL27849876 | 0.74 | ADH1C (0.30) | ADH1AADH1CADH4 | |
| SCHEMBL29958626 | 0.72 | ADH1A (0.47) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL10170018 | 0.72 | SIGMAR1 (0.38) | ADH1AADH1CALDH1A1SMN1; SMN2THRA | |
| SCHEMBL95342 | 0.71 | ADH1A (0.42) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL10171077 | 0.70 | SIGMAR1 (0.41) | ADH1AADH1CALDH1A1SMN1; SMN2THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7560473-B2 | Amine derivative with potassium channel regulatory function, its preparation and use | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES, P.L.A. (CN) | 2009-07-14 | — | — | US | disclosed |
| US-20040266822-A1 | Amine derivative with potassium channel regulatory function, its preparation and use | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. (CN) | 2004-12-30 | — | — | US | disclosed |
| EP-1386908-A1 | AMINE DERIVATIVE WITH POTASSIUM CHANNEL REGULATORY FUNCTION, ITS PREPARATION AND USE | Institute of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A. (CN) | 2004-02-04 | — | — | EP | disclosed |
| US-5239003-A | PROCESS FOR PREPARATION OF STYRENE RESIN COMPOSITION AND STYRENE RESIN COMPOSITION | NIPPON ZEON CO., LTD. (JP) | 1993-08-24 | — | — | US | disclosed |
| US-5155161-A | Living polymer modified by lactam, urea, amino ketone or aldehyde or thio analogs, followed by hydrolysis | NIPPON ZEON CO., LTD. (JP) | 1992-10-13 | — | — | US | disclosed |
| EP-0488346-A1 | Process for preparation of styrene resin composition and styrene resin composition | NIPPON ZEON CO., LTD. (JP) | 1992-06-03 | — | — | EP | disclosed |
| US-4950719-A | LOW TEMPERATURE VIBRATION INSULATOR | NIPPON ZEON CO., LTD. (JP) | 1990-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266822-A1 | Amine derivative with potassium channel regulatory function, its preparation and use | KCNMA1, KCNA5, KCNA1 | ADH1A 451/4885ADH1C 328/4885ADH4 1158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.