Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538257 | 0.93 | KMT2A (0.49) | KMT2ASMN1; SMN2MEN1GAAMAPT | |
| SCHEMBL9537713 | 0.86 | KMT2A (0.55) | KMT2ASMN1; SMN2MEN1GAAMAPT | |
| SCHEMBL9536562 | 0.85 | OPRK1 (0.44) | KMT2ASMN1; SMN2MEN1GAAKDM4E | |
| SCHEMBL9727384 | 0.84 | KMT2A (0.67) | KMT2ASMN1; SMN2MEN1GAAMAPT | |
| SCHEMBL9383304 | 0.83 | KMT2A (0.54) | KMT2ASMN1; SMN2MEN1GAAMAPT | |
| SCHEMBL9535443 | 0.82 | KMT2A (0.43) | KMT2ASMN1; SMN2MEN1GAAMAPT | |
| SCHEMBL9539327 | 0.82 | OPRK1 (0.42) | KMT2ASMN1; SMN2MEN1TSHRTDP1 | |
| SCHEMBL9538662 | 0.80 | SMN1; SMN2 (0.41) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 | |
| SCHEMBL9539291 | 0.80 | KMT2A (0.44) | KMT2ASMN1; SMN2MEN1GAAKDM4E | |
| SCHEMBL8315952 | 0.79 | KMT2A (0.47) | KMT2ASMN1; SMN2MEN1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355599-B1 | 3-ARYL-PYRROLIDINE-2,4-DIONES | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |
| EP-0355599-A1 | 3-Aryl-pyrrolidine-2,4-diones | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |