Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 9/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538257 | 0.90 | KMT2A (0.49) | OPRK1OPRM1HPGDKMT2AMEN1 | |
| SCHEMBL9539327 | 0.85 | OPRK1 (0.42) | OPRK1OPRM1HPGDKMT2AMEN1 | |
| SCHEMBL9534208 | 0.85 | KMT2A (0.60) | KMT2AMEN1SMN1; SMN2TDP1NPC1 | |
| SCHEMBL9534996 | 0.85 | OPRK1 (0.40) | OPRK1OPRM1HPGD | |
| SCHEMBL9727572 | 0.83 | KMT2A (0.49) | OPRK1OPRM1HPGDKMT2AMEN1 | |
| SCHEMBL9535882 | 0.83 | HPGD (0.41) | OPRK1OPRM1HPGDKMT2AMEN1 | |
| SCHEMBL9536216 | 0.82 | ALDH1A1 (0.38) | OPRK1OPRM1HPGDKMT2AMEN1 | |
| SCHEMBL9539291 | 0.81 | KMT2A (0.44) | OPRK1OPRM1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9535560 | 0.81 | TSHR (0.38) | OPRK1OPRM1HPGDKMT2AMEN1 | |
| SCHEMBL9536573 | 0.81 | MEN1 (0.43) | OPRK1OPRM1HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355599-B1 | 3-ARYL-PYRROLIDINE-2,4-DIONES | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |
| EP-0355599-A1 | 3-Aryl-pyrrolidine-2,4-diones | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |