SCHEMBL9534293

SCHEMBL9534293

[c]1nccc(-c2ccccn2)c1-c1ccccn1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.48
LMNA P02545 3/20 0.48
CCR1 P32246 3/20 0.48
CCR5 P51681 3/20 0.48
CCR8 P51685 3/20 0.48
CYP1A2 P05177 1/20 0.48
POLB P06746 1/20 0.48
METAP1 P53582 1/20 0.48
BLM P54132 1/20 0.48
HIF1A Q16665 1/20 0.48
DOHH Q9BU89 1/20 0.48
P4HTM Q9NXG6 1/20 0.48
TP53 P04637 4/20 0.47
TDP1 Q9NUW8 3/20 0.47
NPC1 O15118 6/20 0.42
RAB9A P51151 5/20 0.42
ALOX15 P16050 4/20 0.42
L3MBTL1 Q9Y468 4/20 0.42
SMN1; SMN2 Q16637 4/20 0.42
HTT P42858 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7572110 0.83 KDM1A (0.40) KDM4ELMNACCR1CCR5CCR8
SCHEMBL5695904 0.83 KDM4E (0.43) KDM4ELMNACCR1CCR5CCR8
SCHEMBL11695494 0.79 KDM4E (0.46) KDM4ELMNACCR1CCR5CCR8
SCHEMBL1641797 0.79 KDM4E (0.46) KDM4ELMNACCR1CCR5CCR8
SCHEMBL6787273 0.79 KDM4E (0.47) KDM4ELMNACCR1CCR5CCR8
SCHEMBL28361802 0.79 KDM4E (0.46) KDM4ELMNACCR1CCR5CCR8
SCHEMBL558146 0.75 SMN1; SMN2 (0.46) KDM4ELMNACCR1CCR5CCR8
SCHEMBL7450197 0.75 KDM4E (0.42) KDM4ELMNACCR1CCR5CCR8
SCHEMBL221158 0.74 KDM4E (0.45) KDM4ELMNACCR1CCR5CCR8
SCHEMBL3363096 0.73 KDM4E (0.48) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180248145-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2018-08-30 US claimed
EP-3367456-A1 ORGANIC LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2018-08-29 EP claimed
US-20180166634-A1 ORGANIC LIGHT-EMITTING DEVICE AND COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2018-06-14 US claimed
US-4720502-A Aryl(aryloxy or arylthio)azolomethanes and their use as pesticides THE DOW CHEMICAL COMPANY (US) 1988-01-19 US claimed
US-20240081087-A1 LIGHT-EMITTING DEVICE, METHOD OF MANUFACTURING THE LIGHT-EMITTING DEVICE, AND METHOD OF OPERATING THE LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2024-03-07 US disclosed
EP-4185564-A1 TRICYCLIC HETEROCYCLES Merck Patent GmbH (DE) 2023-05-31 EP disclosed
WO-2023072974-A1 TRICYCLIC HETEROCYCLES MERCK PATENT GMBH (DE) 2023-05-04 WO disclosed
US-11569452-B2 Organic light-emitting device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-01-31 US disclosed
EP-4121423-A1 TETRAZOLE DERIVATIVES Merck Patent GmbH (DE) 2023-01-25 EP disclosed
EP-4121429-A1 CONDENSED PYRIDINE DERIVASTIVES SUBSTITUED BY AMIDE FUNCTIONS AS ACSS2 INHIBITORS Merck Patent GmbH (DE) 2023-01-25 EP disclosed
EP-4053927-A1 LIGHT-EMITTING DEVICE, METHOD OF MANUFACTURING THE SAME, AND OPERATING METHOD OF THE SAME Samsung Electronics Co., Ltd. (KR) 2022-09-07 EP disclosed
WO-2021249969-A1 COMBINATION PRODUCT FOR THE TREATMENT OF CANCER DISEASES MERCK PATENT GMBH (DE) 2021-12-16 WO disclosed
US-20180166634-A1 ORGANIC LIGHT-EMITTING DEVICE AND COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2018-06-14 US disclosed
EP-3294728-A1 SUBSTITUTED QUINOXALINE DERIVATIVES SELVITA S.A. (PL) 2018-03-21 EP disclosed
EP-3294729-A1 SUBSTITUTED QUINOXALINE DERIVATIVES SELVITA S.A. (PL) 2018-03-21 EP disclosed
WO-2016180536-A1 SUBSTITUTED QUINOXALINE DERIVATIVES SELVITA S.A. (PL) 2016-11-17 WO disclosed
WO-2016180537-A1 SUBSTITUTED QUINOXALINE DERIVATIVES SELVITA S.A. (PL) 2016-11-17 WO disclosed
CN-1227229-C Ethylene derivatives and pesticides containing the same NISSAN CHEMICAL IND LTD (JP) 2005-11-16 CN disclosed
EP-0543930-A1 ARTHROPODICIDAL PYRAZOLINES, PYRAZOLIDINES AND HYDRAZINES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-06-02 EP disclosed
WO-1992003421-A2 ARTHROPODICIDAL PYRAZOLINES, PYRAZOLIDINES AND HYDRAZINES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-03-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11569452-B2 Organic light-emitting device CRY1, TRPA1, CRY2 KDM4E 4495/4885LMNA 3687/4885CCR1 3342/4885
US-20180166634-A1 ORGANIC LIGHT-EMITTING DEVICE AND COMPOUND L1CAM, OR10J3, EML4 KDM4E 1971/4885LMNA 1410/4885CCR1 2858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.