Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL659651 | 0.83 | MEN1 (0.38) | MAPT | |
| SCHEMBL8874422 | 0.76 | TDO2 (0.31) | TDO2 | |
| SCHEMBL9534322 | 0.68 | TDO2 (0.31) | TDO2 | |
| SCHEMBL660265 | 0.68 | KDM4E (0.41) | TDO2KDM4EMAPTHIF1AHSD17B10 | |
| SCHEMBL11246263 | 0.67 | TDO2 (0.33) | TDO2HSD17B10 | |
| SCHEMBL6721158 | 0.66 | EP300 (0.44) | HSD17B10 | |
| SCHEMBL5505676 | 0.62 | SMN1; SMN2 (0.52) | MAPTHSD17B10 | |
| SCHEMBL9428376 | 0.62 | — | — | |
| SCHEMBL31179133 | 0.61 | AXL (0.44) | MAPT | |
| SCHEMBL5448026 | 0.61 | GAA (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4120068-A | — | — | None | — | — | JP | disclosed |
| JP-H04120068-A | 4,7-DIAMINOBENZOTHIADIAZOLE DERIVATIVE AND PRODUCTION THEREOF | FUJI XEROX CO LTD | 1992-04-21 | — | — | JP | disclosed |