Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.37 |
| ▸ | PPOX | P50336 | 2/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 4/20 | 0.34 |
| ▸ | PPARD | Q03181 | 3/20 | 0.34 |
| ▸ | PPARA | Q07869 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 4/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529358 | 0.88 | KDM4E (0.35) | KDM4EALDH1A1HSD17B10PTGDR2PPOX | |
| SCHEMBL9530079 | 0.84 | PTGDR2 (0.41) | KDM4EALDH1A1HSD17B10PTGDR2PPOX | |
| SCHEMBL9696171 | 0.80 | KDM4E (0.34) | KDM4EALDH1A1HSD17B10PTGDR2PPOX | |
| SCHEMBL9696140 | 0.78 | LMNA (0.34) | KDM4EALDH1A1PPOXHPGDTSHR | |
| SCHEMBL6911659 | 0.76 | PTGDR2 (0.37) | KDM4EALDH1A1HSD17B10PTGDR2PPOX | |
| SCHEMBL9857238 | 0.75 | KDM4E (0.36) | KDM4EALDH1A1HSD17B10PTGDR2PPOX | |
| SCHEMBL9530495 | 0.74 | NR1H4 (0.36) | KDM4EALDH1A1HSD17B10PTGDR2PPOX | |
| SCHEMBL9534173 | 0.73 | PTGDR2 (0.39) | KDM4EALDH1A1HSD17B10PTGDR2HPGD | |
| SCHEMBL9530763 | 0.72 | PPOX (0.38) | ALDH1A1PPOX | |
| SCHEMBL9530862 | 0.72 | PPOX (0.35) | ALDH1A1PPOXTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542872-A1 | HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES | MONSANTO COMPANY (US) | 1993-05-26 | — | — | EP | disclosed |