Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | PPOX | P50336 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 5/20 | 0.32 |
| ▸ | PPARD | Q03181 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 3/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696171 | 0.90 | KDM4E (0.34) | KDM4EALDH1A1HSD17B10HPGDPTGDR2 | |
| SCHEMBL9530079 | 0.90 | PTGDR2 (0.41) | KDM4EALDH1A1HSD17B10HPGDPTGDR2 | |
| SCHEMBL9696140 | 0.89 | LMNA (0.34) | KDM4EALDH1A1HPGDTSHRPPOX | |
| SCHEMBL9534405 | 0.88 | KDM4E (0.37) | KDM4EALDH1A1HSD17B10HPGDPTGDR2 | |
| SCHEMBL6911659 | 0.83 | PTGDR2 (0.37) | KDM4EALDH1A1HSD17B10HPGDPTGDR2 | |
| SCHEMBL9696367 | 0.83 | KDM4E (0.31) | KDM4E | |
| SCHEMBL9530563 | 0.82 | PTGS2 (0.39) | KDM4EALDH1A1HSD17B10HPGDTSHR | |
| SCHEMBL9857238 | 0.82 | KDM4E (0.36) | KDM4EALDH1A1HSD17B10HPGDPTGDR2 | |
| SCHEMBL9534173 | 0.82 | PTGDR2 (0.39) | KDM4EALDH1A1HSD17B10HPGDPTGDR2 | |
| SCHEMBL9530862 | 0.80 | PPOX (0.35) | ALDH1A1TSHRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542872-A1 | HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES | MONSANTO COMPANY (US) | 1993-05-26 | — | — | EP | claimed |
| WO-1992002509-A1 | HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES | MONSANTO COMPANY (US) | 1992-02-20 | — | — | WO | claimed |
| EP-0542872-A1 | HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES | MONSANTO COMPANY (US) | 1993-05-26 | — | — | EP | disclosed |
| WO-1992002509-A1 | HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES | MONSANTO COMPANY (US) | 1992-02-20 | — | — | WO | disclosed |