Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696178 | 0.88 | KIT (0.37) | MAPTSMN1; SMN2ALDH1A1POLB | |
| SCHEMBL9530563 | 0.87 | PTGS2 (0.39) | PPOXPTGS2MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9534173 | 0.87 | PTGDR2 (0.39) | ALDH1A1TSHR | |
| SCHEMBL8356733 | 0.87 | PGK1 (0.35) | — | |
| SCHEMBL9696367 | 0.83 | KDM4E (0.31) | PTGS2 | |
| SCHEMBL9531683 | 0.82 | PGK1 (0.32) | — | |
| SCHEMBL9531883 | 0.81 | ALDH1A1 (0.34) | PPOXPTGS2MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9529358 | 0.80 | KDM4E (0.35) | PPOXALDH1A1TSHR | |
| SCHEMBL5922945 | 0.80 | — | — | |
| SCHEMBL9530417 | 0.80 | RORC (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542872-A1 | HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES | MONSANTO COMPANY (US) | 1993-05-26 | — | — | EP | disclosed |