Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534241 | 0.86 | PKM (0.50) | ALDH1A1KDM4EHPGDHSD17B10CYP1A2 | |
| SCHEMBL9533900 | 0.80 | KDM4E (0.43) | ALDH1A1KDM4EHPGDRECQLHSD17B10 | |
| SCHEMBL9537313 | 0.79 | GAA (0.52) | HPGDHSD17B10CYP1A2TDP1PKM | |
| SCHEMBL9533007 | 0.77 | ALDH1A1 (0.55) | ALDH1A1KDM4EHPGDHSD17B10TDP1 | |
| SCHEMBL9536991 | 0.76 | CYP1A2 (0.50) | ALDH1A1KDM4EHPGDCYP1A2TDP1 | |
| SCHEMBL9770496 | 0.76 | CYP1A2 (0.43) | ALDH1A1KDM4EHPGDHSD17B10CYP1A2 | |
| SCHEMBL10696259 | 0.75 | CYP1A2 (0.43) | ALDH1A1KDM4EHPGDHSD17B10CYP1A2 | |
| SCHEMBL10993060 | 0.71 | NPC1 (0.45) | ALDH1A1KDM4EHPGDRECQLHSD17B10 | |
| SCHEMBL6704339 | 0.69 | KDM4E (0.54) | ALDH1A1KDM4EHPGDHSD17B10CYP1A2 | |
| SCHEMBL9534033 | 0.68 | PKM (0.50) | ALDH1A1KDM4EHPGDHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263523-B1 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF AG (DE) | 1993-12-29 | — | — | EP | disclosed |
| EP-0263523-A2 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF Aktiengesellschaft (DE) | 1988-04-13 | — | — | EP | disclosed |