Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 4/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534426 | 0.86 | ALDH1A1 (0.43) | PKML3MBTL1CYP1A2TDP1LMNA | |
| SCHEMBL9537313 | 0.82 | GAA (0.52) | PKMCYP1A2TDP1LMNAMAPT | |
| SCHEMBL9536991 | 0.79 | CYP1A2 (0.50) | PKML3MBTL1CYP1A2TDP1LMNA | |
| SCHEMBL9770496 | 0.79 | CYP1A2 (0.43) | PKMCYP1A2TDP1LMNAKMT2A | |
| SCHEMBL9535677 | 0.79 | TDP1 (0.50) | PKML3MBTL1CYP1A2TDP1LMNA | |
| SCHEMBL9534033 | 0.78 | PKM (0.50) | PKML3MBTL1CYP1A2TDP1LMNA | |
| SCHEMBL10696259 | 0.78 | CYP1A2 (0.43) | PKML3MBTL1CYP1A2TDP1LMNA | |
| SCHEMBL9533606 | 0.76 | TNKS (0.43) | CYP1A2MAPTCYP1A1CYP1B1ADORA2A | |
| SCHEMBL9536686 | 0.75 | KDM4E (0.59) | CYP1A2MAPTKMT2ACYP1A1CYP1B1 | |
| SCHEMBL6704339 | 0.72 | KDM4E (0.54) | L3MBTL1CYP1A2TDP1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263523-B1 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF AG (DE) | 1993-12-29 | — | — | EP | disclosed |
| US-5030727-A | Reacting an anthronilide derivative with a thiazole derivative or a fluorozuinazolone with a neucleophile | BASF AKTIENGESELLSCHAFT (DE) | 1991-07-09 | — | — | US | disclosed |
| EP-0263523-A2 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF Aktiengesellschaft (DE) | 1988-04-13 | — | — | EP | disclosed |