Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.44 |
| ▸ | SELE | P16581 | 1/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GCK | P35557 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538024 | 0.79 | PDE7A (0.65) | ALDH1A1MAPTPOLBL3MBTL1KMT2A | |
| SCHEMBL9537872 | 0.78 | HPGD (0.59) | ALDH1A1MAPTPOLBL3MBTL1HPGD | |
| SCHEMBL9536481 | 0.77 | ALDH1A1 (0.43) | ALDH1A1MAPTPOLBL3MBTL1KMT2A | |
| SCHEMBL9538507 | 0.77 | PTGS2 (0.55) | ALDH1A1MAPTPOLBKMT2AHPGD | |
| SCHEMBL29356488 | 0.76 | ALDH1A1 (0.80) | ALDH1A1MAPTPOLBL3MBTL1KMT2A | |
| SCHEMBL4880369 | 0.76 | ALDH1A1 (0.61) | ALDH1A1MAPTPOLBL3MBTL1KMT2A | |
| SCHEMBL9535335 | 0.74 | MAPT (0.53) | ALDH1A1MAPTPOLBL3MBTL1KMT2A | |
| SCHEMBL9535794 | 0.74 | CREBBP (0.40) | ALDH1A1MAPTPOLBL3MBTL1GAA | |
| SCHEMBL1338872 | 0.73 | ALDH1A1 (0.51) | ALDH1A1MAPTPOLBL3MBTL1KMT2A | |
| SCHEMBL27271667 | 0.73 | ALDH1A1 (0.50) | ALDH1A1MAPTPOLBL3MBTL1ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |