Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 8/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536561 | 0.84 | MAPT (0.57) | HPGDALDH1A1MAPTL3MBTL1POLB | |
| SCHEMBL6516644 | 0.82 | MAPT (0.62) | HPGDALDH1A1MAPTL3MBTL1POLB | |
| SCHEMBL6524817 | 0.81 | HPGD (0.59) | HPGDALDH1A1MAPTL3MBTL1POLB | |
| SCHEMBL9535335 | 0.80 | MAPT (0.53) | HPGDALDH1A1MAPTL3MBTL1POLB | |
| SCHEMBL11554461 | 0.80 | ALDH1A1 (0.62) | HPGDALDH1A1MAPTL3MBTL1POLB | |
| SCHEMBL6519708 | 0.79 | HPGD (0.57) | HPGDALDH1A1MAPTL3MBTL1POLB | |
| SCHEMBL6513664 | 0.79 | HPGD (0.57) | HPGDALDH1A1MAPTL3MBTL1POLB | |
| SCHEMBL6513656 | 0.79 | HPGD (0.57) | HPGDALDH1A1MAPTL3MBTL1POLB | |
| SCHEMBL9534492 | 0.78 | ALDH1A1 (0.48) | HPGDALDH1A1MAPTL3MBTL1POLB | |
| SCHEMBL9535339 | 0.78 | L3MBTL1 (0.51) | ALDH1A1MAPTL3MBTL1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0292979-B1 | NEW ALKANESULFONANILIDE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| US-5034417-A | Antiinflammatory agents or analgesics | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-23 | — | — | US | disclosed |
| EP-0292979-A2 | New alkanesulfonanilide derivatives, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-30 | — | — | EP | disclosed |