Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3R2 | O00459 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 4/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 4/20 | 0.32 |
| ▸ | AURKA | O14965 | 2/20 | 0.31 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.31 |
| ▸ | CDK1 | P06493 | 2/20 | 0.31 |
| ▸ | PIM1 | P11309 | 2/20 | 0.31 |
| ▸ | CDK2 | P24941 | 2/20 | 0.31 |
| ▸ | SYK | P43405 | 2/20 | 0.31 |
| ▸ | CLK2 | P49760 | 2/20 | 0.31 |
| ▸ | GSK3A | P49840 | 2/20 | 0.31 |
| ▸ | GSK3B | P49841 | 2/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.31 |
| ▸ | CAMK2B | Q13554 | 2/20 | 0.31 |
| ▸ | CAMK2G | Q13555 | 2/20 | 0.31 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.31 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533212 | 0.79 | PARP1 (0.40) | PTGS2AKR1B1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9532712 | 0.75 | CYP1A2 (0.53) | PIK3R2DYRK1ACLK4SMN1; SMN2MEN1 | |
| SCHEMBL9536487 | 0.68 | PTGS2 (0.36) | PTGS2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9536068 | 0.67 | KDM4E (0.50) | PIK3R2SMN1; SMN2 | |
| SCHEMBL9770716 | 0.65 | PARP1 (0.44) | PTGS2SMN1; SMN2 | |
| SCHEMBL15840739 | 0.64 | PIK3R2 (0.49) | PIK3R2AURKADAPK3CDK1PIM1 | |
| SCHEMBL29003796 | 0.62 | MAPT (0.37) | PTGS2CHEK2RPS6KA3SMN1; SMN2 | |
| SCHEMBL10696348 | 0.62 | PDE10A (0.43) | PIK3R2 | |
| Hydrochloric Acid SCHEMBL10991236 | 0.61 | PTGS2 (0.33) | PTGS2 | |
| Hydrochloric Acid SCHEMBL10991233 | 0.61 | ALDH1A1 (0.31) | PTGS2AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0263523-B1 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF AG (DE) | 1993-12-29 | — | — | EP | disclosed |
| EP-0263523-A2 | Process for the preparation of thiazolo [2,3-b] quinazolones | BASF Aktiengesellschaft (DE) | 1988-04-13 | — | — | EP | disclosed |