Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | CASP9 | P55211 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 3/20 | 0.38 |
| ▸ | ATAD2 | Q6PL18 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535754 | 0.79 | PDE1A (0.56) | ADORA1ALDH1A1LMNATSHRPDE4A | |
| SCHEMBL9534851 | 0.79 | RXFP1 (0.49) | PIK3CDPIK3CAPIK3CBPIK3CGALDH1A1 | |
| SCHEMBL9534736 | 0.79 | PIK3CD (0.43) | PIK3CDPIK3CAPIK3CBPIK3CGCASP7 | |
| SCHEMBL9535004 | 0.79 | PIK3CG (0.40) | PIK3CDPIK3CAPIK3CBPIK3CGADORA2A | |
| SCHEMBL21911024 | 0.79 | ADORA2A (0.42) | PIK3CDPIK3CAPIK3CBPIK3CGADORA2A | |
| SCHEMBL9972910 | 0.77 | PIK3CD (0.41) | PIK3CDPIK3CAPIK3CBPIK3CGCASP7 | |
| SCHEMBL9972896 | 0.77 | PIK3CD (0.41) | PIK3CDPIK3CAPIK3CBPIK3CGCASP7 | |
| SCHEMBL9535041 | 0.77 | KDM4E (0.43) | PIK3CDPIK3CAPIK3CBPIK3CGCASP7 | |
| SCHEMBL9534801 | 0.76 | PIK3CD (0.40) | PIK3CDPIK3CAPIK3CBPIK3CGALDH1A1 | |
| SCHEMBL9535691 | 0.73 | ALDH1A1 (0.45) | ADORA2AADORA2BALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244352-B1 | Pyrido[4,3-d]pyrimidine derivatives | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-31 | — | — | EP | claimed |
| US-4808618-A | ANTIALLERGENS | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1989-02-28 | — | — | US | claimed |
| EP-0244352-B1 | Pyrido[4,3-d]pyrimidine derivatives | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1993-03-31 | — | — | EP | disclosed |
| US-4808618-A | ANTIALLERGENS | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1989-02-28 | — | — | US | disclosed |
| EP-0244352-A2 | Pyrido[4,3-d]pyrimidine derivatives | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1987-11-04 | — | — | EP | disclosed |