Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.35 |
| ▸ | HTR1B | P28222 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536573 | 0.90 | MEN1 (0.43) | FKBP1AOPRK1OPRM1MEN1KMT2A | |
| SCHEMBL9538662 | 0.88 | SMN1; SMN2 (0.41) | FKBP1AOPRK1OPRM1MEN1KMT2A | |
| SCHEMBL9535404 | 0.86 | MEN1 (0.38) | FKBP1AOPRK1OPRM1MEN1KMT2A | |
| SCHEMBL9538119 | 0.85 | TSHR (0.36) | FKBP1AOPRK1OPRM1MEN1KMT2A | |
| SCHEMBL9535560 | 0.85 | TSHR (0.38) | OPRK1OPRM1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9727238 | 0.83 | FKBP1A (0.56) | FKBP1AMEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL9538148 | 0.83 | KMT2A (0.42) | OPRK1OPRM1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9535123 | 0.83 | TSHR (0.37) | FKBP1AOPRK1OPRM1MEN1KMT2A | |
| SCHEMBL9536216 | 0.82 | ALDH1A1 (0.38) | FKBP1AOPRK1OPRM1MEN1KMT2A | |
| SCHEMBL9539291 | 0.81 | KMT2A (0.44) | OPRK1OPRM1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355599-B1 | 3-ARYL-PYRROLIDINE-2,4-DIONES | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |
| EP-0355599-A1 | 3-Aryl-pyrrolidine-2,4-diones | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |