Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538119 | 0.93 | TSHR (0.36) | TSHRNPSR1OPRK1OPRM1MEN1 | |
| SCHEMBL9536216 | 0.90 | ALDH1A1 (0.38) | OPRK1OPRM1MEN1KMT2AALDH1A1 | |
| SCHEMBL9536573 | 0.88 | MEN1 (0.43) | TSHROPRK1OPRM1MEN1KMT2A | |
| SCHEMBL9535123 | 0.88 | TSHR (0.37) | TSHRNPSR1OPRK1OPRM1MEN1 | |
| SCHEMBL9538662 | 0.86 | SMN1; SMN2 (0.41) | OPRK1OPRM1MEN1KMT2AALDH1A1 | |
| SCHEMBL9536709 | 0.86 | OPRK1 (0.36) | TSHRNPSR1OPRK1OPRM1MEN1 | |
| SCHEMBL9538264 | 0.86 | PLA2G1B (0.38) | OPRK1OPRM1MEN1KMT2AALDH1A1 | |
| SCHEMBL9535087 | 0.85 | FKBP1A (0.39) | OPRK1OPRM1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9539327 | 0.84 | OPRK1 (0.42) | TSHROPRK1OPRM1MEN1KMT2A | |
| SCHEMBL9538148 | 0.83 | KMT2A (0.42) | TSHROPRK1OPRM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355599-B1 | 3-ARYL-PYRROLIDINE-2,4-DIONES | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |