Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 7/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537450 | 0.92 | GHSR (0.47) | GHSRPOLBTSHRSCN9AALDH1A1 | |
| SCHEMBL9533421 | 0.90 | SCN9A (0.49) | GHSRPOLBTSHRSCN9AALDH1A1 | |
| SCHEMBL9535341 | 0.86 | GPBAR1 (0.54) | POLBTSHRALDH1A1GPBAR1MAPT | |
| SCHEMBL9536053 | 0.82 | SCN9A (0.53) | GHSRPOLBTSHRSCN9AALDH1A1 | |
| SCHEMBL9535030 | 0.81 | GHSR (0.46) | GHSRSCN9AALDH1A1SCN5ALMNA | |
| SCHEMBL9535545 | 0.81 | FFAR4 (0.50) | GHSRGPBAR1 | |
| SCHEMBL9533922 | 0.80 | TSHR (0.59) | POLBTSHRSCN9AALDH1A1GAA | |
| SCHEMBL6081703 | 0.78 | GHSR (0.62) | GHSRPOLBTSHRALDH1A1GAA | |
| SCHEMBL9535597 | 0.77 | NR1H4 (0.53) | GHSRPOLBTSHR | |
| SCHEMBL9538135 | 0.76 | SMN1; SMN2 (0.48) | GHSRPOLBSCN9AALDH1A1SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573883-A1 | Utilization of 3 substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives against endoparasites new 3-substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives and process for their preparation | BAYER AG (DE) | 1993-12-15 | — | — | EP | disclosed |