Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535220 | 0.92 | GHSR (0.51) | GHSRSCN9ASCN5AMAPTPOLB | |
| SCHEMBL9536053 | 0.91 | SCN9A (0.53) | GHSRSMN1; SMN2SCN9ASCN5AMAPT | |
| SCHEMBL9534075 | 0.84 | SMN1; SMN2 (0.43) | GHSRSMN1; SMN2SCN9ASCN5AMAPT | |
| SCHEMBL9538135 | 0.84 | SMN1; SMN2 (0.48) | GHSRSMN1; SMN2SCN9ASCN5AMAPT | |
| SCHEMBL9536365 | 0.82 | LMNA (0.57) | SMN1; SMN2SCN9AMAPTTP53POLB | |
| SCHEMBL9533421 | 0.82 | SCN9A (0.49) | GHSRSCN9ASCN5AMAPTPOLB | |
| SCHEMBL9535341 | 0.81 | GPBAR1 (0.54) | SMN1; SMN2MAPTTP53POLBALDH1A1 | |
| SCHEMBL9533125 | 0.80 | KMT2A (0.48) | GHSRSMN1; SMN2SCN9APOLBKMT2A | |
| SCHEMBL9535030 | 0.77 | GHSR (0.46) | GHSRSMN1; SMN2SCN9ASCN5ALMNA | |
| SCHEMBL9535545 | 0.76 | FFAR4 (0.50) | GHSRSMN1; SMN2GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573883-A1 | Utilization of 3 substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives against endoparasites new 3-substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives and process for their preparation | BAYER AG (DE) | 1993-12-15 | — | — | EP | disclosed |