Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | CTRC | Q99895 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533905 | 0.86 | ALPL (0.43) | ALPLCTRCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9534377 | 0.86 | MEN1 (0.42) | ALPLCTRCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20719027 | 0.85 | AKR1C3 (0.44) | ALPLCTRCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9534853 | 0.82 | PPARG (0.40) | ALPLCTRCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9535412 | 0.81 | PPARG (0.41) | ALPLCTRCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20719450 | 0.80 | CTSA (0.41) | ALPLCTRCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20718980 | 0.80 | PTGER3 (0.56) | ALPLCTRCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9535997 | 0.79 | CD274 (0.39) | — | |
| SCHEMBL9534841 | 0.78 | MEN1 (0.41) | ALPLCTRCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9536049 | 0.78 | KDM4E (0.49) | KDM4EALDH1A1HPGDPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532531-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-03-24 | — | — | EP | disclosed |
| WO-1991017987-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-11-28 | — | — | WO | disclosed |