Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CD274 | Q9NZQ7 | 14/20 | 0.44 |
| ▸ | PDCD1LG2 | Q9BQ51 | 12/20 | 0.44 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.41 |
| ▸ | PPARA | Q07869 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9537762 | 0.88 | KDM4E (0.49) | KDM4EALDH1A1HPGDCD274PDCD1LG2 | |
| SCHEMBL9535997 | 0.86 | CD274 (0.39) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL9537527 | 0.86 | CD274 (0.47) | KDM4EALDH1A1HPGDCD274PDCD1LG2 | |
| SCHEMBL9537485 | 0.79 | CD274 (0.47) | KDM4EALDH1A1HPGDCD274PDCD1LG2 | |
| SCHEMBL9535376 | 0.78 | ALPL (0.43) | KDM4EALDH1A1HPGDPPARGPPARA | |
| SCHEMBL27473924 | 0.74 | MAPT (0.47) | KDM4EALDH1A1HPGDCD274PDCD1LG2 | |
| SCHEMBL28948611 | 0.73 | ALOX5 (0.52) | KDM4EALDH1A1HPGDPPARGPPARA | |
| SCHEMBL9536294 | 0.73 | CD274 (0.42) | KDM4ECD274PDCD1LG2PDCD1KMT2A | |
| SCHEMBL9533834 | 0.70 | ALDH1A1 (0.52) | KDM4EALDH1A1HPGDCD274PDCD1LG2 | |
| SCHEMBL14376212 | 0.70 | ALDH1A1 (0.50) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532531-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-03-24 | — | — | EP | disclosed |
| WO-1991017987-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-11-28 | — | — | WO | disclosed |