Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | CDC25C | P30307 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | CTRC | Q99895 | 1/20 | 0.39 |
| ▸ | CCNC | P24863 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9534841 | 0.88 | MEN1 (0.41) | MEN1KMT2AALPLJAK2JAK3 | |
| SCHEMBL20719656 | 0.87 | MEN1 (0.41) | MEN1KMT2AALPLJAK2JAK3 | |
| SCHEMBL9535376 | 0.86 | ALPL (0.43) | ALPLCTRCSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9536294 | 0.81 | CD274 (0.42) | KMT2ACDC25BKDM4EL3MBTL1PDCD1LG2 | |
| SCHEMBL9534853 | 0.81 | PPARG (0.40) | MEN1KMT2AALPLCDC25ACDC25B | |
| SCHEMBL20719062 | 0.80 | SLC6A2 (0.39) | MEN1KMT2AALPLJAK2JAK3 | |
| SCHEMBL9537527 | 0.80 | CD274 (0.47) | KDM4EALDH1A1HPGDPDCD1LG2CD274 | |
| SCHEMBL20719844 | 0.78 | ALDH1A1 (0.53) | MEN1KMT2AALPLJAK2JAK3 | |
| SCHEMBL9535007 | 0.78 | MEN1 (0.50) | MEN1KMT2AALPLJAK2JAK3 | |
| SCHEMBL9533905 | 0.78 | ALPL (0.43) | ALPLCTRCSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532531-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-03-24 | — | — | EP | disclosed |
| WO-1991017987-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-11-28 | — | — | WO | disclosed |