Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 14/20 | 0.39 |
| ▸ | PDCD1LG2 | Q9BQ51 | 12/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.37 |
| ▸ | SQOR | Q9Y6N5 | 2/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536049 | 0.86 | KDM4E (0.49) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL9536294 | 0.86 | CD274 (0.42) | CD274PDCD1LG2BTKPDCD1L3MBTL1 | |
| SCHEMBL9535376 | 0.79 | ALPL (0.43) | — | |
| SCHEMBL9533890 | 0.78 | CD274 (0.46) | CD274PDCD1LG2BTKPDCD1SQOR | |
| SCHEMBL9537762 | 0.74 | KDM4E (0.49) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL9537527 | 0.73 | CD274 (0.47) | CD274PDCD1LG2PDCD1 | |
| SCHEMBL9538604 | 0.71 | CD274 (0.45) | CD274PDCD1LG2BTKPDCD1L3MBTL1 | |
| SCHEMBL9535637 | 0.68 | PTGER3 (0.39) | — | |
| SCHEMBL9754460 | 0.67 | KDM4E (0.43) | BTKL3MBTL1 | |
| SCHEMBL9534377 | 0.66 | MEN1 (0.42) | CD274PDCD1LG2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532531-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-03-24 | — | — | EP | disclosed |
| WO-1991017987-A1 | PHENOL AND PYRIDINOL DERIVATIVES AS PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1991-11-28 | — | — | WO | disclosed |