Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5242546 | 0.88 | KMT2A (0.56) | KMT2AMEN1GAAPTGS1PTGS2 | |
| SCHEMBL9533383 | 0.87 | GPBAR1 (0.51) | KMT2AMEN1POLBMAPK1GPBAR1 | |
| SCHEMBL27495331 | 0.86 | KMT2A (0.55) | KMT2AMEN1GAAPTGS1PTGS2 | |
| SCHEMBL9533615 | 0.81 | HSD17B10 (0.59) | GAAPTGS1PTGS2POLBGPBAR1 | |
| SCHEMBL9532926 | 0.81 | PTGS1 (0.54) | KMT2AMEN1GAAPTGS1PTGS2 | |
| SCHEMBL9535442 | 0.80 | GPBAR1 (0.51) | KMT2AMEN1GAAPOLBTSHR | |
| SCHEMBL9533922 | 0.79 | TSHR (0.59) | KMT2AGAAPTGS2POLBTSHR | |
| SCHEMBL9536170 | 0.78 | MAPT (0.52) | KMT2AMEN1PTGS2POLBTSHR | |
| SCHEMBL9535755 | 0.77 | ALDH1A1 (0.52) | GAAPTGS2MAPK1SMN1; SMN2 | |
| SCHEMBL27744385 | 0.77 | PTGS2 (0.59) | KMT2AMEN1GAAPTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573883-A1 | Utilization of 3 substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives against endoparasites new 3-substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives and process for their preparation | BAYER AG (DE) | 1993-12-15 | — | — | EP | disclosed |