Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 5/20 | 0.57 |
| ▸ | NOS1 | P29475 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NOS3 | P29474 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.49 |
| ▸ | HTR3B | O95264 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.49 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536529 | 0.91 | NOS2 (0.55) | NOS2NOS1ALDH1A1NOS3MEN1 | |
| Hydrochloric Acid SCHEMBL9539255 | 0.90 | NOS2 (0.54) | NOS2NOS1ALDH1A1NOS3MEN1 | |
| SCHEMBL9537472 | 0.89 | NOS2 (0.53) | NOS2NOS1ALDH1A1NOS3MEN1 | |
| SCHEMBL11275811 | 0.87 | NOS2 (0.58) | NOS2NOS1ALDH1A1NOS3MEN1 | |
| SCHEMBL9698789 | 0.86 | NOS2 (0.59) | NOS2NOS1ALDH1A1NOS3MEN1 | |
| SCHEMBL8128050 | 0.85 | NOS2 (0.53) | NOS2NOS1ALDH1A1NOS3MEN1 | |
| SCHEMBL7981649 | 0.85 | KDM4E (0.58) | NOS2NOS1ALDH1A1NOS3MEN1 | |
| SCHEMBL9385026 | 0.85 | NOS2 (0.51) | NOS2NOS1ALDH1A1NOS3MEN1 | |
| SCHEMBL9535285 | 0.85 | OPRM1 (0.41) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL11278989 | 0.84 | LMNA (0.55) | NOS2NOS1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282133-B1 | 1-ALKYL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-07-28 | — | — | EP | disclosed |
| US-4943580-A | ANTIALLERGENS | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-07-24 | — | — | US | disclosed |