Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536526 | 0.86 | NR4A2 (0.47) | OPRM1OPRD1OPRK1CNR2MAPT | |
| SCHEMBL9536525 | 0.85 | MAPT (0.42) | OPRM1OPRD1OPRK1RETMAPT | |
| SCHEMBL9537229 | 0.85 | SSTR5 (0.56) | MAPTKDM4EPOLBNR4A2KCNH2 | |
| SCHEMBL9535525 | 0.85 | NOS2 (0.57) | MAPTKDM4EHTR3EHTR3BHTR3A | |
| SCHEMBL9535868 | 0.84 | SLC6A9 (0.44) | RETMAPTKDM4EKCNH2 | |
| SCHEMBL11473098 | 0.84 | SSTR5 (0.52) | OPRM1OPRD1OPRK1MAPTPDE4B | |
| Hydrochloric Acid SCHEMBL10384124 | 0.84 | SLC6A9 (0.44) | RETMAPTKDM4EKCNH2 | |
| SCHEMBL10697050 | 0.82 | MAPT (0.44) | OPRM1OPRD1OPRK1MAPTPDE4B | |
| SCHEMBL9535360 | 0.82 | HRH1 (0.54) | OPRM1OPRD1OPRK1MAPTHTR1A | |
| SCHEMBL11480609 | 0.81 | SSTR5 (0.57) | OPRM1OPRD1OPRK1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282133-B1 | 1-ALKYL SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-07-28 | — | — | EP | disclosed |
| US-4943580-A | ANTIALLERGENS | JANSSEN PHARMACEUTICA N.V. (BE) | 1990-07-24 | — | — | US | disclosed |
| EP-0282133-A2 | 1-alkyl substituted benzimidazole derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1988-09-14 | — | — | EP | disclosed |