Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7439627 | 0.76 | SCN1A (0.33) | L3MBTL1 | |
| SCHEMBL7436705 | 0.74 | L3MBTL1 (0.37) | L3MBTL1PTPN1TSHRCYP3A4CYP2D6 | |
| SCHEMBL9134829 | 0.71 | L3MBTL1 (0.41) | L3MBTL1PTPN1TSHRCYP3A4CYP2D6 | |
| SCHEMBL9132471 | 0.69 | TSHR (0.49) | TSHRPOLBTRPA1 | |
| SCHEMBL9133864 | 0.69 | GABRA1 (0.42) | TSHRPOLBCYP3A4GAASMN1; SMN2 | |
| SCHEMBL1824047 | 0.69 | SMN1; SMN2 (0.50) | L3MBTL1TSHRPOLBCYP3A4GAA | |
| SCHEMBL5664115 | 0.69 | TSHR (0.52) | L3MBTL1TSHRPOLBTRPA1BCL2 | |
| SCHEMBL9099802 | 0.68 | SMN1; SMN2 (0.57) | L3MBTL1TSHRPOLBCYP3A4CYP2D6 | |
| SCHEMBL7435318 | 0.68 | SCN1A (0.38) | L3MBTL1PTPN1TSHRCYP3A4CYP2D6 | |
| SCHEMBL6546378 | 0.67 | L3MBTL1 (0.46) | L3MBTL1CYP3A4CYP2D6CYP2C19BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532693-A1 | 1,4-DIAMINO-2,3-DIHYDROXYBUTANES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-03-24 | — | — | EP | disclosed |