Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | LDHB | P07195 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9134829 | 0.87 | L3MBTL1 (0.41) | L3MBTL1CYP2D6CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL7432982 | 0.86 | SMN1; SMN2 (0.37) | L3MBTL1CYP2D6CYP1A2TSHRHTT | |
| SCHEMBL7444181 | 0.82 | TSHR (0.38) | L3MBTL1CYP2D6CYP2C19CYP1A2CYP2C9 | |
| SCHEMBL7445854 | 0.80 | SCN1A (0.36) | L3MBTL1CYP2D6CYP2C19TSHRCYP3A4 | |
| SCHEMBL7444375 | 0.78 | TRPA1 (0.39) | CYP1A2TSHRCYP3A4TRPA1 | |
| SCHEMBL7438300 | 0.76 | S1PR1 (0.35) | L3MBTL1LDHALDHBCYP2D6CYP2C19 | |
| SCHEMBL7435318 | 0.75 | SCN1A (0.38) | L3MBTL1LDHALDHBCYP2D6CYP2C19 | |
| SCHEMBL9540262 | 0.74 | KDM4E (0.44) | L3MBTL1CYP2D6CYP1A2CYP2C9TSHR | |
| SCHEMBL9130891 | 0.74 | TRPA1 (0.36) | TSHRPTPN1TRPA1 | |
| SCHEMBL9535770 | 0.74 | L3MBTL1 (0.38) | L3MBTL1CYP2D6CYP2C19TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491149-A | VIRICIDES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-02-13 | — | — | US | disclosed |