SCHEMBL7435318

SCHEMBL7435318

CC(C)c1c(Cc2ccccc2)cccc1[C](Cc1ccccc1)C1CC1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SCN1A P35498 1/20 0.38
SCN2A Q99250 1/20 0.38
SCN3A Q9NY46 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.36
LDHA P00338 1/20 0.35
LDHB P07195 1/20 0.35
CYP2D6 P10635 2/20 0.34
CYP2C19 P33261 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
TSHR P16473 2/20 0.33
ALDH1A1 P00352 1/20 0.33
GLA P06280 1/20 0.33
HPGD P15428 1/20 0.33
CYP3A4 P08684 1/20 0.33
HRH1 P35367 2/20 0.33
LMNA P02545 1/20 0.33
PTPN1 P18031 1/20 0.32
CAPN1 P07384 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7432308 0.96 SCN1A (0.37) SCN1ASCN2ASCN3AL3MBTL1LDHA
SCHEMBL7370889 0.83 SCN1A (0.44) SCN1ASCN2ASCN3AL3MBTL1CYP2D6
SCHEMBL7446846 0.79 TSHR (0.39) SCN1ASCN2ASCN3ACYP2D6CYP2C19
SCHEMBL9130434 0.79 LMNA (0.38) L3MBTL1TSHRALDH1A1GLAHPGD
SCHEMBL7436359 0.77 SUCNR1 (0.38) L3MBTL1
SCHEMBL7446176 0.76 ALDH1A1 (0.40) CYP2D6ALDH1A1GLAHPGDLMNA
SCHEMBL7439021 0.75 SCN1A (0.36) SCN1ASCN2ASCN3ACYP2D6CYP2C19
SCHEMBL7436705 0.75 L3MBTL1 (0.37) L3MBTL1LDHALDHBCYP2D6CYP2C19
SCHEMBL9132381 0.71 TSHR (0.44) L3MBTL1TSHRALDH1A1GLAHPGD
SCHEMBL6547623 0.70 LDHA (0.48) L3MBTL1LDHALDHBCYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5491149-A VIRICIDES THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-02-13 US disclosed