Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | AGXT | P21549 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538832 | 0.75 | GAA (0.43) | GPR55ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL6159073 | 0.74 | MAOB (0.46) | ALDH1A1GAAMPOSMN1; SMN2 | |
| SCHEMBL9538789 | 0.74 | ALDH1A1 (0.46) | ALDH1A1IDO1GAASMN1; SMN2 | |
| SCHEMBL3451026 | 0.73 | ALDH1A1 (0.34) | ALDH1A1IDO1GAASMN1; SMN2 | |
| SCHEMBL13255465 | 0.72 | HPGD (0.50) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL3788490 | 0.72 | GAA (0.40) | CNR1CNR2GPR55ALDH1A1GAA | |
| SCHEMBL3038603 | 0.71 | GAA (0.69) | GPR55ALDH1A1GAA | |
| SCHEMBL8218381 | 0.71 | LTA4H (0.44) | ALDH1A1IDO1AGXTMPO | |
| SCHEMBL9535642 | 0.71 | SMN1; SMN2 (0.43) | CNR1CNR2GPR55ALDH1A1GAA | |
| SCHEMBL29454280 | 0.70 | CNR1 (0.43) | CNR1CNR2GPR55ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0151826-B1 | 4-[(Bicyclic heterocyclyl)-methyl and -hetero]-piperidines | JANSSEN PHARMACEUTICA N.V. (BE) | 1993-03-31 | — | — | EP | disclosed |