Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535404 | 0.88 | MEN1 (0.38) | SMN1; SMN2MEN1KMT2AL3MBTL1OPRM1 | |
| SCHEMBL9538264 | 0.87 | PLA2G1B (0.38) | SMN1; SMN2MEN1KMT2AL3MBTL1OPRM1 | |
| SCHEMBL8317692 | 0.86 | POLB (0.35) | SMN1; SMN2GAAALOX12MEN1KMT2A | |
| SCHEMBL9536573 | 0.85 | MEN1 (0.43) | SMN1; SMN2MEN1KMT2AOPRM1OPRK1 | |
| SCHEMBL8317561 | 0.85 | CYP3A4 (0.35) | SMN1; SMN2GAAALOX12MEN1KMT2A | |
| SCHEMBL8316152 | 0.84 | POLB (0.37) | SMN1; SMN2GAAALOX12MEN1KMT2A | |
| SCHEMBL9536709 | 0.83 | OPRK1 (0.36) | SMN1; SMN2MEN1KMT2AOPRM1OPRK1 | |
| SCHEMBL9727473 | 0.83 | FKBP1A (0.47) | SMN1; SMN2MEN1KMT2APOLB | |
| SCHEMBL8312553 | 0.83 | ALDH1A1 (0.40) | SMN1; SMN2GAAALOX12MEN1KMT2A | |
| SCHEMBL9538321 | 0.83 | SIGMAR1 (0.49) | MEN1KMT2AOPRM1OPRK1UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0355599-B1 | 3-ARYL-PYRROLIDINE-2,4-DIONES | BAYER AG (DE) | 1993-05-19 | — | — | EP | disclosed |
| EP-0355599-A1 | 3-Aryl-pyrrolidine-2,4-diones | BAYER AG (DE) | 1990-02-28 | — | — | EP | disclosed |