Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 4/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417108 | 0.86 | GAA (0.45) | SYKSERPINE1CTSKATMGAA | |
| SCHEMBL3648358 | 0.86 | CTSK (0.49) | SYKCTSKATMPTPN11CTSS | |
| SCHEMBL9938243 | 0.84 | CTSS (0.46) | SYKCTSKATMCTSSMALT1 | |
| SCHEMBL165863 | 0.82 | SYK (0.41) | SYKSERPINE1CTSKCTSSPCSK9 | |
| SCHEMBL1760230 | 0.82 | NPC1 (0.43) | SYKSERPINE1CTSKCTSSPCSK9 | |
| SCHEMBL3996179 | 0.81 | GAA (0.41) | CTSKGAA | |
| SCHEMBL6167126 | 0.80 | KDM4A (0.44) | SYKCTSKCTSSMALT1MEN1 | |
| SCHEMBL9533724 | 0.78 | SYK (0.51) | SYKMEN1KMT2A | |
| SCHEMBL4367633 | 0.78 | SERPINE1 (0.39) | SYKSERPINE1CTSKATMCTSS | |
| SCHEMBL3654576 | 0.77 | CTSS (0.46) | SYKSERPINE1CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532693-A1 | 1,4-DIAMINO-2,3-DIHYDROXYBUTANES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-03-24 | — | — | EP | disclosed |